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Dr. Barbara A. Han

Disease Ecologist | PhD, Oregon State University

Expertise
machine learning, behavioral ecology, macroecology

External site: www.hanlab.science | Profile (pdf)

Twitter: @bahanbug

845 677-7600 x135

Barbara Han’s research is at the intersection of ecology, computing, and global health. Han uses machine learning to forecast outbreaks of new zoonotic diseases – those that ‘jump’ from animals to humans. Of more than a billion cases of human illness reported each year, the majority are attributed to zoonotic pathogens.

Han employs complex computer algorithms to analyze patterns and processes in nature that could result in the next Ebola, SARS, or West Nile virus outbreak. Some of these models compare traits of known animal disease carriers — size, diet, reproductive habits, biogeography — with thousands of species not yet known to carry disease, in order to predict which animals might become disease carriers in the future. Han also works on projects that predict where and when diseases could emerge; other research investigates why and how some species transmit more zoonoses to humans than others.

Research like Han’s has the potential to become a valuable tool for public health officials. Predicting and preempting the arrival of a new zoonotic disease will save lives. This technology could also impact land management decisions, as it becomes obvious that diseases are more likely to emerge from certain habitats.

Han has partnered with diverse collaborators at IBM and NASA to advance research on global disease prediction. She contributes to efforts led by the World Health Organization, Coalition for Epidemic Preparedness Innovations, Wellcome Trust, and multiple US governmental agencies to apply this research to disease preemption. She is on the Board on Life Sciences at the National Academies of Sciences, Engineering, and Medicine, which provides guidance on life sciences-related issues to the US government and the public.

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Fischhoff, Ilya R., Tao Huang, Stephen K. Hamilton, Barbara A. Han, Shannon L. LaDeau, Richard S. Ostfeld, Emma J. Rosi, and Christopher T. Solomon. 2020. “Parasite and Pathogen Effects on Ecosystem Processes: A Quantitative Review”. Ecosphere 11 (5). Wiley. doi:10.1002/ecs2.3057.
Han, Barbara A., Suzanne M. O’Regan, John Paul Schmidt, and John M. Drake. 2020. “Integrating Data Mining and Transmission Theory in the Ecology of Infectious Diseases”. Edited by Amanda Bates. Ecology Letters 23 (8). Wiley: 1178-88. doi:10.1111/ele.13520.
Berger, Kavita, James Wood, Bonnie Jenkins, Jennifer Olsen, Stephen Morse, Louise Gresham, J. Root, et al. 2019. “Policy and Science for Global Health Security: Shaping the Course of International Health”. Tropical Medicine and Infectious Disease 4 (2): 60. doi:10.3390/tropicalmed4020060.
Han, Barbara A., S. Majumdar, F. P. Calmon, B. S. Glicksberg, R. Horesh, A. Kumar, A. Perer, et al. 2019. “Confronting Data Sparsity to Identify Potential Sources of Zika Virus Spillover Infection Among Primates”. Epidemics 27: 59-65. doi:10.1016/j.epidem.2019.01.005.
Plowright, Raina K., Daniel J. Becker, Daniel E. Crowley, Alex D. Washburne, Tao Huang, P. O. Nameer, Emily S. Gurley, and Barbara A. Han. 2019. “Prioritizing Surveillance of Nipah Virus in India”. PLOS Neglected Tropical Diseases 13 (6): e0007393. doi:10.1371/journal.pntd.0007393.
Pandit, Pranav, and Barbara A. Han. 2019. “Rise of Machines in Disease Ecology”. The Bulletin of the Ecological Society of America 101 (1). Wiley. doi:10.1002/bes2.1625.
Downs, Cynthia J., Laura A. Schoenle, Barbara A. Han, Jon F. Harrison, and Lynn B. Martin. 2019. “Scaling of Host Competence”. Trends in Parasitology 35 (3): 182-92. doi:10.1016/j.pt.2018.12.002.
Schmidt, John Paul, Sean Maher, John M. Drake, Tao Huang, Maxwell J. Farrell, and Barbara A. Han. 2019. “Ecological Indicators of Mammal Exposure to Ebolavirus”. Philosophical Transactions of the Royal Society B: Biological Sciences 374 (1782). The Royal Society: 20180337. doi:10.1098/rstb.2018.0337.
Han, Barbara A., and Richard S. Ostfeld. 2019. “Topic Modeling of Major Research Themes in Disease Ecology of Mammals”. Journal of Mammalogy 100 (3). Oxford University Press (OUP): 1008-18. doi:10.1093/jmammal/gyy174.
Stephens, Patrick R., Sonia Altizer, Vanessa O. Ezenwa, John L. Gittleman, Emili Moan, Barbara A. Han, Shan Huang, and Paula Pappalardo. 2019. “Parasite Sharing in Wild Ungulates and Their Predators: Effects of Phylogeny, Range Overlap, and Trophic Links”. Journal of Animal Ecology 88 (7). Wiley: 1017-28. doi:10.1111/1365-2656.12987.
Almeida, Rafael M., Barbara A. Han, Alexander J. Reisinger, Catherine Kagemann, and Emma J. Rosi. 2018. “High Mortality in Aquatic Predators of Mosquito Larvae Caused by Exposure to Insect Repellent”. Biology Letters 14 (10): 20180526. doi:10.1098/rsbl.2018.0526.
Dallas, Tad A., Barbara A. Han, Charles L. Nunn, Andrew W. Park, Patrick R. Stephens, and John M. Drake. 2018. “Host Traits Associated With Species Roles in Parasite Sharing Networks”. Oikos 128 (1): 23-32. doi:10.1111/oik.05602.
Strona, G., C. J. Carstens, P. S. A. Beck, and Barbara A. Han. 2018. “The Intrinsic Vulnerability of Networks to Epidemics”. Ecological Modelling 383: 91-97. doi:10.1016/j.ecolmodel.2018.05.013.
Walker, Joseph, Barbara A. Han, Isabel M. Ott, and John M. Drake. 2018. “Transmissibility of Emerging Viral Zoonoses”. PLOS ONE 13 (11): e0206926. doi:10.1371/journal.pone.0206926.
Yang, Laura H., and Barbara A. Han. 2018. “Data-Driven Predictions and Novel Hypotheses about Zoonotic Tick Vectors from the Genus Ixodes”. BMC Ecology 183 (1). doi:10.1186/s12898-018-0163-2.
Blaustein, Andrew, Jenny Urbina, Paul Snyder, Emily Reynolds, Trang Dang, Jason Hoverman, Barbara A. Han, Deanna Olson, Catherine Searle, and Natalie Hambalek. 2018. “Effects of Emerging Infectious Diseases on Amphibians: A Review of Experimental Studies”. Diversity 10 (3): 81. doi:10.3390/d10030081.
Dallas, Tad A., A. Aguirre, Sarah A. Budischak, Colin Carlson, V.O. Ezenwa, Barbara A. Han, Shan Huang, and Patrick R. Stephens. 2018. “Gauging Support for Macroecological Patterns in Helminth Parasites”. Global Ecology and Biogeography 27 (12): 1437-47. doi:10.1111/geb.12819.
NeCamp, Timothy, Prasanna Sattigeri, Dennis Wei, Emily Ray, Youssef Drissi, Ananya Poddar, Diwakar Mahajan, et al. (2017) 2017. “ Cognitive Disease Hunter: Developing Automated Pathogen Feature Extraction from Scientific Literature”. In Data Science for Social Good Conference. Chicago, IL. https://pdfs.semanticscholar.org/151b/c458cc3433151a7695d2a9109068217b3613.pdf.
Evans, Michelle V., Tad A. Dallas, Barbara A. Han, Courtney C. Murdock, and John M. Drake. 2017. “Data-Driven Identification of Potential Zika Virus Vectors”. ELife 6. doi:10.7554/eLife.22053.
Stephens, Patrick R., Paula Pappalardo, Shan Huang, J.E. Byers, Maxwell J. Farrell, Alyssa Gehman, Ria R. Ghai, et al. 2017. “Global Mammal Parasite Database Version 2.0”. Ecology 98 (5): 1476-76. doi:10.1002/ecy.1799.
adrian castellanos

Dr. Adrian Castellanos is the data manager and spatial analyst in the Han lab, where he supports data visualization and scripting. He received his PhD in Wildlife and Fisheries Sciences from Texas A&M University working with Dr. Jessica Light. This work focused on how natural history collections can be used to examine patterns of biodiversity and biogeography in Central American mammals, highlighting the continued importance of specimen collection and data digitization. Although he identifies as a mammalogist, Adrian has also worked on birds, amphibians, orthopterans, and ticks with projects involving disease ecology, behavioral plasticity, morphological shape change, cryptic diversity, and species distribution and occupancy modeling. His research interests include improving species distribution modeling for conservation and biodiversity work, biodiversity informatics, and helping write and troubleshoot code.

 
July Pilowsky

Dr. July Pilowsky is a postdoctoral scientist in the Han lab, applying a process-explicit modeling approach to analyzing the ecology of infectious diseases and their hosts. They have a background in animal behavior, conservation biology, and ecological modeling. They received their PhD through a joint program between the University of Adelaide in Australia and the University of Copenhagen in Denmark, researching and developing process-explicit ecological models. They applied this technique to reconstruct the range collapses of the extinct steppe bison and the currently threatened European bison over tens of thousands of years. They have developed / co-developed two R packages for ecological modeling: colorednoise, which models temporal autocorrelation, and paleopop, which models species range dynamics over long timescales.